The Mote host consists of a USB controller, with four channels, that connects via a USB A to micro B cable to your computer, and up to four APA102 RGB LED strips with 16 pixels on each (for a total of 64 pixels per USB controller, although the firmware can theoretically handle 128 pixels per channel).
The USB controller can be powered straight from your computer, but we've provided a power boost port to which you can connect a 2+A power supply, to boost the pixel brightness to retina-searing levels.
Of course, you can have several USB controllers running on the same computer, so your only real limitation is providing enough power.
Pimoroni has designed the Mote to work equally well with whatever flavour of computer you have, be it Linux (inc. Raspberry Pi 3, 2 or B+), Mac, or Windows.
If you're looking for a more compact solution, ideal for the Pi Zero, then there's also Mote pHAT that lets you control your Mote sticks directly through your Pi's GPIO.